Benzodiazepines

 

 
 
What are Benzodiazepines?
 
Benzodiazepines are medications that are frequently prescribed for the symptomatic treatment of anxiety and sleep disorders.  They produce their effects via specific receptors involving a neurochemical called gamma aminobutyric acid (GABA).
Because they are safer and more effective, Benzodiazepines have replaced barbiturates in the treatment of both anxiety and insomnia.  Benzodiazepines are also used as sedatives before some surgical and medical procedures, and for the
treatment of seizure disorders and alcohol withdrawal.  Risk of physical dependence increases if Benzodiazepines are taken regularly (e.g. daily ) for more than a few months, especially at higher then normal doses.  Stopping abruptly can bring
on such symptoms as trouble sleeping, gastrointestinal upset, feeling unwell, loss of appetite, sweating, trembling, weakness, anxiety and changes in perception.  Only trace amounts (less than 1%) of most Benzodiazepines are excreted unaltered
in the urine; most of the concentration in urine is conjugated drug.  The detection period for the Benzodiazepines in the urine is 3-7 days.
 
- Benzodiazepines are central nervous system depressants that are commonly known as tranquilizers, sedatives, or anxiolytics.
 
- Benzodiazepines enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA receptor, resulting in sedative, hypnotic (sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant properties.
 
- High doses of many shorter-acting benzodiazepines may also cause anterograde amnesia and dissociation.
 
- These properties make benzodiazepines useful in treating anxiety, insomnia, agitation, seizures, muscle spasms, alcohol withdrawal and as a premedication for medical or dental procedures
 
Types of Benzodiazepines:
 
- Alprazolam
           - Xanax        
- Clonazepam
           - Klonopin
          - Rivotril
          - Valpax
- Nordiazepam
           - Valium
          - Diazepam
          - Valrelease
- Oxazepam
           - Serax
- Temazepan
           - Restoril
- Lorazepam
           - Temesta
          - Ativan
- Flurazepam
           - Dalmane
- Flunitrazepam
          - Narcozep
          - Rohipnol
          - Roipnol
 
Street Names:
 
Benzos
- Blue V
- Candy
- Downers
- Sleeping Pills
- Tranks
- Rohypnol

- Roofies
- Roofinol
- Rope
- Rophies
 
Detection Periods:
 
Urine = 1-6 Weeks
 
​Blood = 6-48 Hours
 
Saliva = 1-10 Days
 
Hair = Up to 90 Days
 
 
What It's Prescribed For:
 
Anxiety
- Insomnia
- Alcohol withdrawal
- Seizure control
- Muscle relaxation
- Inducing amnesia for uncomfortable procedures
- Given before an anesthetic (such as before surgery)
 
 
Possible Side Effects:
 
- Drowsiness
- Confusion
- Dizziness
- Blurred vision
- Weakness
- Slurred speech
- Lack of coordination
- Difficulty breathing
- Coma
 
 
Brands: Duragesic, Subsys, Abstral, and Ionsys

Availability: Prescription needed

Pregnancy: Consult a doctor

Alcohol:
 Avoid. Very serious interactions can occur

Drug class: Pain reliever